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Literature summary extracted from
- Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas (2003), J. Biol. Chem., 278, 9784-9789.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.1.2 | L-Pro + NAD(P)+ | Homo sapiens | the enzyme plays a role as a downstream effector in p53-mediated apoptosis of renal carcinoma cells | 1-pyrroline-5-carboxylate + NAD(P)H | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.5.1.2 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.5.1.2 | RCC 786-O cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.5.1.2 | L-Pro + NAD(P)+ | the enzyme plays a role as a downstream effector in p53-mediated apoptosis of renal carcinoma cells | Homo sapiens | 1-pyrroline-5-carboxylate + NAD(P)H | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.5.1.2 | proline oxidase | - |
Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.1.2 | NAD(P)+ | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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