EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.3.5.1 | F69V | mutation in anchor subunit Sdh4, 56% of wild-type kcat | Saccharomyces cerevisiae |
1.3.5.1 | H99L | mutation in anchor subunit Sdh4, 29% of wild-type kcat | Saccharomyces cerevisiae |
1.3.5.1 | S71A | mutation in anchor subunit Sdh4, 43% of wild-type kcat | Saccharomyces cerevisiae |
1.3.5.1 | Y89OCH | substitution with stop codon truncates Sdh4 by removing the third predicted transmembrane segment, 22% of wild-type activity | Saccharomyces cerevisiae |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.3.5.1 | 2-sec-butyl-4,6-dinitrophenol | non-competitive inhibition | Saccharomyces cerevisiae |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.3.5.1 | 0.0037 | - |
2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinone | 22°C | Saccharomyces cerevisiae |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.3.5.1 | membrane | - |
Saccharomyces cerevisiae | 16020 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.5.1 | succinate + ubiquinone | Saccharomyces cerevisiae | - |
fumarate + ubiquinol | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.5.1 | Saccharomyces cerevisiae | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.5.1 | succinate + 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone | - |
Saccharomyces cerevisiae | fumarate + 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinol | - |
? | |
1.3.5.1 | succinate + ubiquinone | - |
Saccharomyces cerevisiae | fumarate + ubiquinol | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.3.5.1 | complex II | - |
Saccharomyces cerevisiae |
1.3.5.1 | SDH | - |
Saccharomyces cerevisiae |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.3.5.1 | 40 | - |
no loss of activity after 10 min | Saccharomyces cerevisiae |
1.3.5.1 | 65 | - |
almost complete loss of activity after 10 min | Saccharomyces cerevisiae |
1.3.5.1 | 68 | - |
approx. 50% loss of activity after 10 min | Saccharomyces cerevisiae |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.3.5.1 | 3.6 | - |
2,3-Dimethoxy-5-methyl-6-decyl-1,4-benzoquinone | 22°C | Saccharomyces cerevisiae |