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Literature summary extracted from

  • Yamashita, Y.; Nishibori, M.; Terada, T.; Isobe, N.; Shimada, M.
    Gonadotropin-induced DELTA14-reductase and DELTA7-reductase gene expression in cumulus cells during meiotic resumption of porcine oocytes (2005), Endocrinology, 146, 186-194.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.3.1.70 additional information enzyme expression is induced by gonadotropin, overview Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.70 AY9944-A-7 enzyme-specific inhibitor, leads to apoptosis in vivo at high concentrations in cumulus cells of oocytes Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.70 follicular fluid meiosis-activating sterol + NADPH Sus scrofa
-
 testicular meiosis-activating sterol + NADP+
-
 ?
1.3.1.70 additional information Sus scrofa enzyme is involved in de novo synthesis of progesterone from lanosterol via cholesterol, pathway overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.70 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.70 additional information enzyme expression is induced by gonadotropin Sus scrofa
-
1.3.1.70 oocyte
-
 Sus scrofa
-
1.3.1.70 ovarian cumulus cell during meiotic resumption of oocytes Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.70 follicular fluid meiosis-activating sterol + NADPH
-
 Sus scrofa testicular meiosis-activating sterol + NADP+
-
 ?
1.3.1.70 additional information enzyme is involved in de novo synthesis of progesterone from lanosterol via cholesterol, pathway overview Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.70 DELTA14-reductase
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.70 NADPH
-
 Sus scrofa