EC Number | Cloned (Comment) | Organism |
---|---|---|
1.2.1.3 | expression by a baculovirus system | Homo sapiens |
1.2.1.3 | expression by a baculovirus system | Oryctolagus cuniculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.2.1.3 | 0.0021 | - |
4-hydroxynonenal | pH 8.0, 25°C | Oryctolagus cuniculus | |
1.2.1.3 | 0.0035 | - |
hexanal | pH 8.0, 25°C | Oryctolagus cuniculus | |
1.2.1.3 | 0.0134 | - |
hexanal | pH 8.0, 25°C | Homo sapiens | |
1.2.1.3 | 0.014 | - |
malondialdehyde | pH 8.0, 25°C | Oryctolagus cuniculus | |
1.2.1.3 | 0.0179 | - |
4-hydroxynonenal | pH 8.0, 25°C | Homo sapiens | |
1.2.1.3 | 0.0662 | - |
propionaldehyde | pH 8.0, 25°C | Oryctolagus cuniculus | |
1.2.1.3 | 0.1144 | - |
malondialdehyde | pH 8.0, 25°C | Homo sapiens | |
1.2.1.3 | 0.1372 | - |
propionaldehyde | pH 8.0, 25°C | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.2.1.3 | 54000 | - |
x * 54000, SDS-PAGE | Homo sapiens |
1.2.1.3 | 54000 | - |
x * 54000, SDS-PAGE | Oryctolagus cuniculus |
1.2.1.3 | 54340 | - |
x * 54340, calculation from nucleotide sequence | Oryctolagus cuniculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.3 | additional information | Homo sapiens | the enzyme may contribute to corneal cellular defense against oxidative damage by metabolizing toxic aldehydes produced during UV-induced lipid peroxidation | ? | - |
? | |
1.2.1.3 | additional information | Oryctolagus cuniculus | the enzyme may contribute to corneal cellular defense against oxidative damage by metabolizing toxic aldehydes produced during UV-induced lipid peroxidation | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.3 | Homo sapiens | - |
- |
- |
1.2.1.3 | Oryctolagus cuniculus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.2.1.3 | - |
Homo sapiens |
1.2.1.3 | - |
Oryctolagus cuniculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.2.1.3 | corneal epithelium | - |
Homo sapiens | - |
1.2.1.3 | corneal epithelium | - |
Oryctolagus cuniculus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.2.1.3 | 0.2341 | - |
substrate: propionaldehyde, pH 8.0, 25°C | Homo sapiens |
1.2.1.3 | 0.5337 | - |
substrate: propionaldehyde, pH 8.0, 25°C | Oryctolagus cuniculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.3 | 4-hydroxynonenal + NAD+ + H2O | - |
Oryctolagus cuniculus | 4-hydroxynonanoate + NADH | - |
? | |
1.2.1.3 | 4-hydroxynonenal + NAD+ + H2O | - |
Homo sapiens | 4-hydroxynonanoate + NADH + H+ | - |
? | |
1.2.1.3 | hexanal + NAD+ + H2O | - |
Homo sapiens | hexanoate + NADH + H+ | - |
? | |
1.2.1.3 | hexanal + NAD+ + H2O | - |
Oryctolagus cuniculus | hexanoate + NADH + H+ | - |
? | |
1.2.1.3 | malondialdehyde + NAD+ + H2O | - |
Homo sapiens | ? + NADH | - |
? | |
1.2.1.3 | malondialdehyde + NAD+ + H2O | - |
Oryctolagus cuniculus | ? + NADH | - |
? | |
1.2.1.3 | additional information | the enzyme may contribute to corneal cellular defense against oxidative damage by metabolizing toxic aldehydes produced during UV-induced lipid peroxidation | Homo sapiens | ? | - |
? | |
1.2.1.3 | additional information | the enzyme may contribute to corneal cellular defense against oxidative damage by metabolizing toxic aldehydes produced during UV-induced lipid peroxidation | Oryctolagus cuniculus | ? | - |
? | |
1.2.1.3 | propanal + NAD+ + H2O | - |
Oryctolagus cuniculus | propionate + NADH | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.2.1.3 | ? | x * 54000, SDS-PAGE | Homo sapiens |
1.2.1.3 | ? | x * 54000, SDS-PAGE | Oryctolagus cuniculus |
1.2.1.3 | ? | x * 54340, calculation from nucleotide sequence | Oryctolagus cuniculus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.2.1.3 | ALDH1A1 | - |
Homo sapiens |
1.2.1.3 | ALDH1A1 | - |
Oryctolagus cuniculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.3 | NAD+ | - |
Homo sapiens | |
1.2.1.3 | NAD+ | - |
Oryctolagus cuniculus |