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Literature summary extracted from

  • Mounaji, K.; Vlassi, M.; Erraiss, N.E.; Wegnez, M.; Serrano, A.; Soukri, A.
    In vitro effect of metal ions on the activity of two amphibian glyceraldehyde-3-phosphate dehydrogenases: potential metal binding sites (2003), Comp. Biochem. Physiol. B, 135B, 241-254.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.12
-
Xenopus laevis
1.2.1.12
-
Pleurodeles waltl

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.12 CdCl2 20 mM, about 30% inhibition. 10 mM, 70% inhibition Pleurodeles waltl
1.2.1.12 CdCl2 20 mM, about 65% inhibition Xenopus laevis
1.2.1.12 CuSO4 0.001 mM, 90% inhibition within 2 min Pleurodeles waltl
1.2.1.12 CuSO4 0.001 mM, 70% inhibition in 2 min Xenopus laevis
1.2.1.12 ZnSO4 20 mM, 70% inhibition Pleurodeles waltl
1.2.1.12 ZnSO4 20 mM, 50% inhibition Xenopus laevis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.12 35000
-
4 * 35000, SDS-PAGE Xenopus laevis
1.2.1.12 37000
-
4 * 37000, SDS-PAGE Pleurodeles waltl

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.12 Pleurodeles waltl Q8AXB5
-
-
1.2.1.12 Xenopus laevis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.12
-
Xenopus laevis
1.2.1.12
-
Pleurodeles waltl

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.12 D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
Xenopus laevis 3-phospho-D-glyceroyl phosphate + NADH
-
?
1.2.1.12 D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
Pleurodeles waltl 3-phospho-D-glyceroyl phosphate + NADH
-
?

Subunits

EC Number Subunits Comment Organism
1.2.1.12 tetramer 4 * 37000, SDS-PAGE Pleurodeles waltl
1.2.1.12 tetramer 4 * 35000, SDS-PAGE Xenopus laevis

Synonyms

EC Number Synonyms Comment Organism
1.2.1.12 GAPDH
-
Xenopus laevis
1.2.1.12 GAPDH
-
Pleurodeles waltl

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.12 NAD+
-
Xenopus laevis
1.2.1.12 NAD+
-
Pleurodeles waltl

pI Value

EC Number Organism Comment pI Value Maximum pI Value
1.2.1.12 Pleurodeles waltl isoelectric focusing
-
6.9
1.2.1.12 Xenopus laevis isoelectric focusing
-
7.1