BRENDA - Enzyme Database

A QM/MM study of a nucleophilic aromatic substitution reaction catalyzed by 4-chlorobenzoyl-CoA dehalogenase

Xu, D.; Guo, H.; Gao, J.; Cui, Q.; Chem. Commun. (Camb.) 2004, 892-893 (2004)
No PubMed abstract available

Data extracted from this reference:

KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.8.1.7
additional information
-
additional information
kinetics, thermodynamics
Bacteria
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.8.1.7
4-chlorobenzoyl-CoA + H2O
Bacteria
-
4-hydroxybenzoyl-CoA + chloride
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.8.1.7
Bacteria
-
-
-
Reaction
EC Number
Reaction
Commentary
Organism
3.8.1.7
4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride
specific for dehalogenation at the 4-position, can dehalogenate substrates bearing fluorine, chlorine, bromine and iodine in the 4-position, SNAr mechanism
Bacteria
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.8.1.7
4-chlorobenzoyl-CoA + H2O
-
655227
Bacteria
4-hydroxybenzoyl-CoA + chloride
-
-
-
?
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.8.1.7
additional information
-
additional information
kinetics, thermodynamics
Bacteria
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.8.1.7
4-chlorobenzoyl-CoA + H2O
Bacteria
-
4-hydroxybenzoyl-CoA + chloride
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.8.1.7
4-chlorobenzoyl-CoA + H2O
-
655227
Bacteria
4-hydroxybenzoyl-CoA + chloride
-
-
-
?