Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Karsten, W.E.; Tipton, P.A.; Cook, P.F.
    Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD (2002), Biochemistry, 41, 12193-12199.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.93 additional information the reaction requires a divalent metal ion for activity Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.93 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.93 (+)-tartrate + NAD+
-
 Escherichia coli oxaloglycolate + NADH + H+
-
 ?
1.1.1.93 D-malate + NAD+ stepwise oxidative decarboxylation, a oxalacetate intermediate is formed Escherichia coli pyruvate + CO2 + NADH + H+
-
 ?
1.1.1.93 D-malate + thio-NAD+
-
 Escherichia coli pyruvate + CO2 + thio-NADH + H+
-
 ?

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.93 additional information
-
 discussion of the pH-rate profile of the reaction with D-malate or (+)-tartrate, the pH dependence of the pyruvate/malate ratio is studied Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.93 NAD+
-
 Escherichia coli
1.1.1.93 thio-NAD+
-
 Escherichia coli