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Literature summary extracted from
- Comparison of ligand polarization and enzyme activation in medium- and short-chain acyl-coenzyme A dehydrogenase-novel analog complexes (2003), Arch. Biochem. Biophys., 409, 251-261.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.3.8.1 | expression in Escherichia coli | Megasphaera elsdenii |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.3.8.7 | additional information | - |
additional information | - |
Sus scrofa |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.3.8.1 | 2-butenoyl-CoA + reduced acceptor | Megasphaera elsdenii | reduction in vivo | butanoyl-CoA + acceptor | - |
r |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.3.8.1 | Megasphaera elsdenii | - |
- |
- |
| 1.3.8.7 | Sus scrofa | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.3.8.1 | recombinant bSCAD | Megasphaera elsdenii |
| 1.3.8.7 | - |
Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.3.8.7 | kidney | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.3.8.1 | 2-butenoyl-CoA + reduced acceptor | reduction in vivo | Megasphaera elsdenii | butanoyl-CoA + acceptor | - |
r | |
| 1.3.8.1 | butanoyl-CoA + acceptor | - |
Megasphaera elsdenii | 2-butenoyl-CoA + reduced acceptor | - |
r | |
| 1.3.8.7 | additional information | substrate/product binding results in ligand polarization and positive flavin potential shifts, which activate the enzyme for electron transfer | Sus scrofa | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.3.8.1 | bSCAD | - |
Megasphaera elsdenii |
| 1.3.8.7 | medium-chain acyl-CoA dehydrogenase | - |
Sus scrofa |
| 1.3.8.7 | medium-chain acyl-coenzyme A dehydrogenase | - |
Sus scrofa |
| 1.3.8.7 | pMCAD | - |
Sus scrofa |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.3.8.7 | FAD | - |
Sus scrofa | |
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Release 2023.1 (January 2023)
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