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Literature summary extracted from

  • Yildiz, O.; Bodur, E.; Cokugras, A.N.; Ozer, N.
    Partial purification and characterization of soluble isoform of butyrylcholinesterase from rat intestine (2004), Protein J., 23, 143-151.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.8 benzoylthiocholine substrate inhibition Rattus norvegicus
3.1.1.8 Triton X-100 inhibition above 0.01 mM Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.8 0.047
-
 Benzoylcholine pH 7.4, 37°C Rattus norvegicus
3.1.1.8 0.06
-
 acetylthiocholine pH 7.4, 37°C Rattus norvegicus
3.1.1.8 0.087
-
 acetylthiocholine pH 7.4, 37°C Rattus norvegicus
3.1.1.8 0.115
-
 propionylthiocholine pH 7.4, 37°C Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.8 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.8 260fold Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.8 intestine
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.8 4612
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.8 acetylthiocholine + H2O increasing activity with substrates in the following order: acetylthiocholine, propionylthiocholine, butyrylthiocholine Rattus norvegicus thiocholine + acetate
-
 ?
3.1.1.8 benzoylcholine + H2O
-
 Rattus norvegicus choline + benzoate
-
 ?
3.1.1.8 butyrylthiocholine + H2O increasing activity with substrates in the following order: acetylthiocholine, propionylthiocholine, butyrylthiocholine Rattus norvegicus thiocholine + butyrate
-
 ?
3.1.1.8 propionylthiocholine + H2O increasing activity with substrates in the following order: acetylthiocholine, propionylthiocholine, butyrylthiocholine Rattus norvegicus thiocholine + propionate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.8 tetramer nonreducing PAGE Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.8 37
-
-
 Rattus norvegicus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.1.1.8 0.005
-
 acetylthiocholine pH 7.4, 37°C Rattus norvegicus
3.1.1.8 16.8
-
 Benzoylcholine pH 7.4, 37°C Rattus norvegicus
3.1.1.8 23.5
-
 acetylthiocholine pH 7.4, 37°C Rattus norvegicus
3.1.1.8 49.2
-
 propionylthiocholine pH 7.4, 37°C Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.8 7.2
-
-
 Rattus norvegicus