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Literature summary extracted from

  • Sakuma, S.; Fujimoto, Y.; Sawada, T.; Saeki, K.; Akimoto, M.; Fujita, T.
    Existence of acyl-CoA hydrolase-mediated pathway supplying arachidonic acid for prostaglandin synthesis in microsomes from rabbit kidney medulla (1999), Prostaglandins, 57, 63-72.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.2.2 lysophosphatidylcholine
-
 Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.2.2 cytosol
-
 Oryctolagus cuniculus 5829
-
3.1.2.2 microsome
-
 Oryctolagus cuniculus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.2 arachidonoyl-CoA + H2O Oryctolagus cuniculus enzyme provides arachidonic acid for prostaglandin synthesis in microsomes of kidney medulla CoA + arachidonate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.2 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.2 kidney medulla Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.2.2 0.16
-
 kidney cortex microsomes, substrate palmitoyl-CoA Oryctolagus cuniculus
3.1.2.2 0.21
-
 kidney cortex microsomes, substrate arachidonoyl-CoA Oryctolagus cuniculus
3.1.2.2 0.26
-
 kidney medulla microsomes, substrate palmitoyl-CoA Oryctolagus cuniculus
3.1.2.2 0.28
-
 kidney cortex cytosol, substrate palmitoyl-CoA Oryctolagus cuniculus
3.1.2.2 0.35
-
 kidney medulla microsomes, substrate arachidonoyl-CoA Oryctolagus cuniculus
3.1.2.2 0.46
-
 kidney medulla cytosol, substrate palmitoyl-CoA Oryctolagus cuniculus
3.1.2.2 0.47
-
 kidney cortex cytosol, substrate arachidonoyl-CoA Oryctolagus cuniculus
3.1.2.2 0.54
-
 kidney medulla cytosol, substrate arachidonoyl-CoA Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.2 arachidonoyl-CoA + H2O
-
 Oryctolagus cuniculus CoA + arachidonate
-
 ?
3.1.2.2 arachidonoyl-CoA + H2O enzyme provides arachidonic acid for prostaglandin synthesis in microsomes of kidney medulla Oryctolagus cuniculus CoA + arachidonate
-
 ?
3.1.2.2 palmitoyl-CoA + H2O
-
 Oryctolagus cuniculus CoA + palmitate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.2.2 acyl-CoA hydrolase
-
 Oryctolagus cuniculus
3.1.2.2 acyl-coenzyme A hydrolase
-
 Oryctolagus cuniculus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.2.2 37
-
 assay at Oryctolagus cuniculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.2.2 8
-
 assay at Oryctolagus cuniculus