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Literature summary extracted from
- Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target (1999), Proc. Natl. Acad. Sci. USA, 96, 7220-7225.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 5.3.99.3 | expression in Escherichia coli | Homo sapiens |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.3.99.3 | membrane | - |
Homo sapiens | 16020 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.99.3 | Homo sapiens | O14684 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.99.3 | (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate + GSH | i.e. prostaglandin H2 | Homo sapiens | (5Z,13E)-(15S)-11alpha,15-dihydroxyprosta-5,13-dienoate + GSSG | i.e. prostaglandin E2 | ? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.3.99.3 | PGE synthase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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