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Literature summary extracted from

  • Garcia-Ayllon, M.S.; Saez-Valero, J.; Munoz-Delgado, E.; Vidal, C.J.
    Identification of hybrid cholinesterase forms consisting of acetyl- and butyrylcholinesterase subunits in human glioma (2001), Neuroscience, 107, 199-208.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.7 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide i.e. BW284c51 Homo sapiens
3.1.1.8 tetraisopropyl diphosphoramide i.e. iso-OMPA Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.7 acetylcholine + H2O Homo sapiens
-
 choline + acetate
-
 ?
3.1.1.8 butyrylcholine + H2O Homo sapiens
-
 choline + butyrate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Homo sapiens
-
-
-
3.1.1.8 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.8 separation from acetylcholine esterase Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.7 astrocytoma cell
-
 Homo sapiens
-
3.1.1.7 brain
-
 Homo sapiens
-
3.1.1.7 cerebral cortex
-
 Homo sapiens
-
3.1.1.7 cyst from astrocytoma Homo sapiens
-
3.1.1.7 oligodendroglioma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetylcholine + H2O
-
 Homo sapiens choline + acetate
-
 ?
3.1.1.8 butyrylcholine + H2O
-
 Homo sapiens choline + butyrate
-
 ?
3.1.1.8 butyrylthiocholine iodide + H2O
-
 Homo sapiens thiocholine iodide + butyrate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.7 tetramer 3 types of tetrameres: 1. ChE-I which contains only butyrylcholinesterase, ChE-II which contains acetyl cholinesterase and butyrylcholinesterase and ChE-III which contains only acetylcholinesterase Homo sapiens
3.1.1.8 tetramer 3 types of tetrameres: 1. ChE-I which contains only butyrylcholinesterase, ChE-II which contains acetyl cholinesterase and butyrylcholinesterase and ChE-III which contains only acetylcholinesterase Homo sapiens