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Literature summary extracted from

  • Erck, C.; Frank, R.; Wehland, J.
    Tubulin-tyrosine ligase, a long-lasting enigma (2000), Neurochem. Res., 25, 5-10.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.2.25 expression of TTL in Escherichia coli and Sf9 insect cells Sus scrofa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.2.25 Mg2+ required for activity Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.3.2.25 43425
-
 1 * 43425, deduced from nucleotide sequence Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.25 ATP + detyrosinated alpha-tubulin + L-tyrosine Sus scrofa
-
 alpha-tubulin + ADP + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.25 Sus scrofa
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
6.3.2.25 phosphoprotein TTL contains a potential serine phosphorylation site for cAMP-dependent protein kinase Sus scrofa

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.2.25
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.25 ATP + detyrosinated alpha-tubulin + L-tyrosine
-
 Sus scrofa alpha-tubulin + ADP + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
6.3.2.25 monomer 1 * 43425, deduced from nucleotide sequence Sus scrofa

Synonyms

EC Number Synonyms Comment Organism
6.3.2.25 TTL
-
 Sus scrofa
6.3.2.25 tubulin tyrosine ligase
-
 Sus scrofa

pI Value

EC Number Organism Comment pI Value Maximum pI Value
6.3.2.25 Sus scrofa predicted from nucleotide sequence
-
 6.51