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Literature summary extracted from

  • Takagi, M.; Yamakawa, H.; Watanabe, T.; Suga, T.; Yamada, J.
    Inducible expression of long-chain acyl-CoA hydrolase gene in cell cultures (2003), Mol. Cell. Biochem., 252, 379-385.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.8.8 transient and stable expression as C-terminally MYC-tagged enzyme in mouse C3H 10T1/2 fibroblastic cells using a mifepristone-inducible gene expression system, analysis of cell growth rates, enzyme expression rates, and effect on phospholipid synthesis, overview Mus musculus
3.1.2.2 BACH, stable expression in C3H 10T1/2 fibroblastic cell line using an mifepristone (RU486)-inducible expression system as C-terminally MYC-tagged enzyme Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.8.8 palmitoyl-CoA + electron-transfer flavoprotein Mus musculus enzyme does not affect all acyl-CoA utilizing cellular processes (2E)-2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?
3.1.2.2 palmitoyl-CoA + H2O Mus musculus the enzyme affects specifically cellular systems and functions, but not all acyl-CoA-utilizing processes, overexpression leads to reduction of growth rate but not to phospholipid synthesis CoA + palmitate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.8 Mus musculus
-
-
-
3.1.2.2 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.8 brain
-
 Mus musculus
-
1.3.8.8 neuron
-
 Mus musculus
-
3.1.2.2 brain
-
 Mus musculus
-
3.1.2.2 neuron
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.8 palmitoyl-CoA + electron-transfer flavoprotein
-
 Mus musculus (2E)-2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?
1.3.8.8 palmitoyl-CoA + electron-transfer flavoprotein enzyme does not affect all acyl-CoA utilizing cellular processes Mus musculus (2E)-2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?
3.1.2.2 palmitoyl-CoA + H2O
-
 Mus musculus CoA + palmitate
-
 ?
3.1.2.2 palmitoyl-CoA + H2O the enzyme affects specifically cellular systems and functions, but not all acyl-CoA-utilizing processes, overexpression leads to reduction of growth rate but not to phospholipid synthesis Mus musculus CoA + palmitate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.8.8 BACH
-
 Mus musculus
1.3.8.8 long-chain acyl-CoA dehydrogenase
-
 Mus musculus
1.3.8.8 More see also EC 3.1.2.2, palmitoyl-CoA hydrolase Mus musculus
3.1.2.2 BACH
-
 Mus musculus
3.1.2.2 long-chain acyl-CoA hydrolase
-
 Mus musculus