Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Cengiz, D.; Cokugras, A.N.; Tezcan, E.F.
    A new perspective on thermal inactivation kinetics of human serum butyrylcholinesterase (2002), J. Protein Chem., 21, 145-149.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.8 Benzoylcholine competitive Homo sapiens
3.1.1.8 choline competitive Homo sapiens
3.1.1.8 Succinylcholine
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.8 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.8 6600fold Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.8 serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.8 butyrylthiocholine + H2O
-
 Homo sapiens thiocholine + butyrate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.8 pseudocholinesterase
-
 Homo sapiens

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.1.1.8 40
-
 incubation for 24 h inactivates the enzyme, 25% loss of activity after 24 h, enzyme can not be reactivated at 4°C Homo sapiens
3.1.1.8 45
-
 incubation for 24 h converts the enzyme to a stabilized form, enzyme can be reactivated by incubation at 4°C Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.8 0.0012
-
 Succinylcholine 45°C Homo sapiens
3.1.1.8 0.0032
-
 Benzoylcholine 37°C Homo sapiens
3.1.1.8 0.005
-
 Succinylcholine 37°C Homo sapiens
3.1.1.8 0.007
-
 Benzoylcholine 45°C Homo sapiens
3.1.1.8 11
-
 choline 37°C Homo sapiens
3.1.1.8 15.89
-
 choline 45°C Homo sapiens