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Literature summary extracted from

  • Bernkop-Schnurch, A.; Zarti, H.; Walker, G.F.
    Thiolation of polycarbophil enhances its inhibition of intestinal brush border membrane bound aminopeptidase N (2001), J. Pharm. Sci., 90, 1907-1914.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.2 cysteine
-
 Sus scrofa
3.4.11.2 additional information
-
 Sus scrofa
3.4.11.2 polycarbophil
-
 Sus scrofa
3.4.11.2 polycarbophil-cysteine conjugates cysteine linked to polycarbophil by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride, strong inhibitor, protects leucine enkephalin against degradation by the enzyme Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.2 brush border
-
 Sus scrofa 5903
-
3.4.11.2 membrane
-
 Sus scrofa 16020
-

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.2 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.2 intestinal mucosa
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.2 L-Leu-4-nitroanilide + H2O synthetic substrate Sus scrofa L-Leu + 4-nitroaniline
-
 ?
3.4.11.2 leucine enkephalin + H2O model peptide drug Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.2 aminopeptidase N
-
 Sus scrofa