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Literature summary extracted from

  • Archontis, G.; Simonson, T.; Moras, D.; Karplus, M.
    Specific amino acid recognition by aspartyl-tRNA synthetase studied by free energy simulations (1998), J. Mol. Biol., 275, 823-846.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.12 ATP + L-aspartate + tRNAAsp Thermus thermophilus specific amino acid binding by the enzyme is required for correct translation of the genetic code AMP + diphosphate + L-aspartyl-tRNAAsp
-
?
6.1.1.12 ATP + L-aspartate + tRNAAsp Escherichia coli specific amino acid binding by the enzyme is required for correct translation of the genetic code AMP + diphosphate + L-aspartyl-tRNAAsp
-
?
6.1.1.12 ATP + L-aspartate + tRNAAsp Saccharomyces cerevisiae specific amino acid binding by the enzyme is required for correct translation of the genetic code AMP + diphosphate + L-aspartyl-tRNAAsp
-
?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.12 Escherichia coli
-
-
-
6.1.1.12 Saccharomyces cerevisiae
-
-
-
6.1.1.12 Thermus thermophilus
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
6.1.1.12 ATP + L-aspartate + tRNAAsp = AMP + diphosphate + L-aspartyl-tRNAAsp mechanism, active site structure, substrate binding, simulations of binding and free energy Thermus thermophilus
6.1.1.12 ATP + L-aspartate + tRNAAsp = AMP + diphosphate + L-aspartyl-tRNAAsp mechanism, active site structure, substrate binding, simulations of binding and free energy Saccharomyces cerevisiae
6.1.1.12 ATP + L-aspartate + tRNAAsp = AMP + diphosphate + L-aspartyl-tRNAAsp mechanism, active site structure, substrate binding, simulations of binding and free energy, protein-ligand modeling Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.12 ATP + L-aspartate + tRNAAsp
-
Thermus thermophilus AMP + diphosphate + L-aspartyl-tRNAAsp
-
?
6.1.1.12 ATP + L-aspartate + tRNAAsp
-
Escherichia coli AMP + diphosphate + L-aspartyl-tRNAAsp
-
?
6.1.1.12 ATP + L-aspartate + tRNAAsp
-
Saccharomyces cerevisiae AMP + diphosphate + L-aspartyl-tRNAAsp
-
?
6.1.1.12 ATP + L-aspartate + tRNAAsp specific amino acid binding by the enzyme is required for correct translation of the genetic code Thermus thermophilus AMP + diphosphate + L-aspartyl-tRNAAsp
-
?
6.1.1.12 ATP + L-aspartate + tRNAAsp specific amino acid binding by the enzyme is required for correct translation of the genetic code Escherichia coli AMP + diphosphate + L-aspartyl-tRNAAsp
-
?
6.1.1.12 ATP + L-aspartate + tRNAAsp specific amino acid binding by the enzyme is required for correct translation of the genetic code Saccharomyces cerevisiae AMP + diphosphate + L-aspartyl-tRNAAsp
-
?
6.1.1.12 additional information erroneous binding of Asn by the enzyme is highly improbable, determination of binding energy Thermus thermophilus ?
-
?
6.1.1.12 additional information erroneous binding of Asn by the enzyme is highly improbable, determination of binding energy Escherichia coli ?
-
?
6.1.1.12 additional information erroneous binding of Asn by the enzyme is highly improbable, determination of binding energy Saccharomyces cerevisiae ?
-
?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.12 Aspartic acid translase
-
Thermus thermophilus
6.1.1.12 Aspartic acid translase
-
Escherichia coli
6.1.1.12 Aspartic acid translase
-
Saccharomyces cerevisiae
6.1.1.12 Aspartyl ribonucleate synthetase
-
Thermus thermophilus
6.1.1.12 Aspartyl ribonucleate synthetase
-
Escherichia coli
6.1.1.12 Aspartyl ribonucleate synthetase
-
Saccharomyces cerevisiae
6.1.1.12 aspartyl ribonuleic synthetase
-
Thermus thermophilus
6.1.1.12 aspartyl ribonuleic synthetase
-
Escherichia coli
6.1.1.12 aspartyl ribonuleic synthetase
-
Saccharomyces cerevisiae
6.1.1.12 Aspartyl-transfer ribonucleic acid synthetase
-
Thermus thermophilus
6.1.1.12 Aspartyl-transfer ribonucleic acid synthetase
-
Escherichia coli
6.1.1.12 Aspartyl-transfer ribonucleic acid synthetase
-
Saccharomyces cerevisiae
6.1.1.12 Aspartyl-transfer RNA synthetase
-
Thermus thermophilus
6.1.1.12 Aspartyl-transfer RNA synthetase
-
Escherichia coli
6.1.1.12 Aspartyl-transfer RNA synthetase
-
Saccharomyces cerevisiae
6.1.1.12 Aspartyl-tRNA synthetase
-
Thermus thermophilus
6.1.1.12 Aspartyl-tRNA synthetase
-
Escherichia coli
6.1.1.12 Aspartyl-tRNA synthetase
-
Saccharomyces cerevisiae