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Literature summary extracted from

  • Gomis-Rueth, F.X.; Gohlke, U.; Betz, M.; Knauper, V.; Murphy, G.; Lopez-Otin, C.; Bode, W.
    The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain (1996), J. Mol. Biol., 264, 556-566.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.4.24.B4 recombinant enzyme, hanging-drop vapour diffusion method, 20 mM Tris-HCl, pH 7.3, 5 mM CaCl2, 300 mM NaCl, addition of 1 M ammonium sulfate solution, pH 9.0, equilibrated against ammonium sulfate at 1.2 M, 20°C, 1 week, X-ray structure determination at 2.7 A resolution and analyis of the C-terminal haemopexin-like domain Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.B4 protein + H2O Homo sapiens enzyme is involved in human breast cancer pathology and in arthritic processes peptides
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.B4 Homo sapiens P45452 recombinant procollagnase expressed in NSO mouse myeloma cells and secreted to the medium
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.B4 protein + H2O
-
 Homo sapiens peptides
-
 ?
3.4.24.B4 protein + H2O enzyme is involved in human breast cancer pathology and in arthritic processes Homo sapiens peptides
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.24.B4 More structure and peptide organization, three-dimensional modeling Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.4.24.B4 M10.013 Merops-ID Homo sapiens
3.4.24.B4 matrix metalloproteinase-13
-
 Homo sapiens
3.4.24.B4 MMP-13
-
 Homo sapiens