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Literature summary extracted from

  • Matsushita, M.; Thiel, S.; Jensenius, J.C.; Terai, I.; Fujita, T.
    Proteolytic activities of two types of mannose-binding lectin-associated serine protease (2000), J. Immunol., 165, 2637-2642.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.B7 C1 inhibitor inhibited in a dose-dependent manner Homo sapiens
3.4.21.104 C1-inhibitor forms equimolar complexes with the enzyme and inhibits its proteolytic activity Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.104 70000
-
 SDS-PAGE, proenzyme form Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.104 Protein + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.B7 Homo sapiens P48740
-
-
3.4.21.104 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.104 serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.B7 complement component C2 + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.B7 complement component C3 + H2O cleavage with appearance of the alpha-chain Homo sapiens ?
-
 ?
3.4.21.B7 additional information no digestion of complement component C4 Homo sapiens ?
-
 ?
3.4.21.104 complement component C2 + H2O activates complement C2 Homo sapiens ?
-
 ?
3.4.21.104 complement component C3 + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.104 complement component C4 + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.104 Protein + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.B7 MASP-1
-
 Homo sapiens
3.4.21.104 MASP-2
-
 Homo sapiens