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Literature summary extracted from
- Substrate specificities of the protease of mouse serum Ra-reactive factor (1995), J. Immunol., 154, 2351-2357.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 3.4.21.B7 | unstable in diluted solutions | Mus musculus |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.21.B7 | 20 | - |
N-carbobenzoxy-L-lysine-4-nitrophenyl ester | pH 6, 25°C | Mus musculus |  |
| 3.4.21.B7 | 33 | - |
N-carbobenzoxy-L-tyrosine-4-nitrophenyl ester | pH 8, 25°C | Mus musculus | |
| 3.4.21.B7 | 1000 | - |
N-carbobenzoxy-L-alanine-4-nitrophenyl ester | pH 8, 25°C | Mus musculus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.B7 | additional information | Mus musculus | involved in activation of complement cascade | ? | - |
? | |
| 3.4.21.B7 | Protein + H2O | Mus musculus | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.B7 | Mus musculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.B7 | serum | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.B7 | alpha-chain of complement C3 + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.B7 | alpha-chain of complement C4 + H2O | preferred substrate | Mus musculus | ? | - |
? | |
| 3.4.21.B7 | additional information | involved in activation of complement cascade | Mus musculus | ? | - |
? | |
| 3.4.21.B7 | N-carbobenzoxy-L-alanine-4-nitrophenyl ester + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.B7 | N-carbobenzoxy-L-lysine-4-nitrophenyl ester + H2O | - |
Mus musculus | N-carbobenzoxy-L-Lys + 4-nitrophenol | - |
? | |
| 3.4.21.B7 | N-carbobenzoxy-L-tyrosine-4-nitrophenyl ester + H2O | - |
Mus musculus | ? | - |
? | |
| 3.4.21.B7 | Protein + H2O | - |
Mus musculus | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.B7 | P100 | - |
Mus musculus |
| 3.4.21.B7 | Ra-reactive factor | complex of multiple polysaccaride-binding subunits associated with serine protease P100 | Mus musculus |
| 3.4.21.B7 | RaRF | - |
Mus musculus |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.B7 | 37 | - |
95% loss of C4-cleaving activity after 30 min in 130 mM NaCl, 2 mM CaCl2, 20 mM Tris, pH8 | Mus musculus |
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