EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.16 | additional information | not: UTP | Clarias batrachus | |
6.3.4.16 | N-acetyl-L-glutamate | - |
Clarias batrachus | |
6.3.5.5 | N-acetyl-L-glutamate | only CPS III | Clarias batrachus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.3.5.5 | UMP | only CPS II | Clarias batrachus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.3.5.5 | 0.46 | - |
L-glutamine | pH 7.5, 30°C | Clarias batrachus | |
6.3.5.5 | 2.2 | - |
ammonia | pH 7.5, 30°C | Clarias batrachus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
6.3.4.16 | mitochondrion | - |
Clarias batrachus | 5739 | - |
6.3.4.16 | mitochondrion | - |
Heteropneustes fossilis | 5739 | - |
6.3.5.5 | cytosol | CPS II | Clarias batrachus | 5829 | - |
6.3.5.5 | mitochondrion | CPS III | Clarias batrachus | 5739 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.16 | ATP + NH3 + CO2 + H2O | Clarias batrachus | first step of the both the urea cycle and pyrimidine nucleotide biosynthesis patways | ADP + phosphate + carbamoyl phosphate | - |
? | |
6.3.5.5 | 2 ATP + L-Gln + HCO3- | Clarias batrachus | enzyme is a key enzyme in the pyrimidine nucleotide and arginine biosynthetic pathways | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.4.16 | Clarias batrachus | - |
- |
- |
6.3.4.16 | Heteropneustes fossilis | - |
- |
- |
6.3.5.5 | Clarias batrachus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.3.5.5 | recombinant wild-type and mutant enzymes | Clarias batrachus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.16 | ATP + NH3 + CO2 + H2O | - |
Heteropneustes fossilis | ADP + phosphate + carbamoyl phosphate | - |
ir | |
6.3.4.16 | ATP + NH3 + CO2 + H2O | first step of the both the urea cycle and pyrimidine nucleotide biosynthesis patways | Clarias batrachus | ADP + phosphate + carbamoyl phosphate | - |
? | |
6.3.4.16 | ATP + NH4+ + CO2 + H2O | - |
Clarias batrachus | ADP + phosphate + carbamoyl phosphate | - |
? | |
6.3.5.5 | 2 ATP + L-Gln + HCO3- | - |
Clarias batrachus | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? | |
6.3.5.5 | 2 ATP + L-Gln + HCO3- | enzyme is a key enzyme in the pyrimidine nucleotide and arginine biosynthetic pathways | Clarias batrachus | 2 ADP + phosphate + L-Glu + carbamoyl phosphate | - |
? | |
6.3.5.5 | 2 ATP + NH4+ + HCO3- | - |
Clarias batrachus | 2 ADP + phosphate + carbamoyl phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.3.4.16 | CPS I-like (ammonia- and N-acetyl-L-glutamate-dependent) | - |
Clarias batrachus |
6.3.4.16 | CPS I-like (ammonia- and N-acetyl-L-glutamate-dependent) | - |
Heteropneustes fossilis |
6.3.5.5 | CPS II (glutamine-dependent) | - |
Clarias batrachus |
6.3.5.5 | CPS III (glutamine- and N-acetyl-L-glutamine-dependent) | - |
Clarias batrachus |