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Literature summary extracted from

  • Reiss, U.; Oskouian, B.; Zhou, J.; Gupta, V.; Sooriyakumaran, P.; Kelly, S.; Wang, E.; Merrill, A.H., Jr.; Saba, J.D.
    Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis (2004), J. Biol. Chem., 279, 1281-1290.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.2.27 fusion protein with green fluorescence protein, expressed in HEK293 cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.2.27 endoplasmic reticulum
-
 Homo sapiens 5783
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.2.27 63480
-
 calculated from amino acid sequence Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.2.27 additional information Homo sapiens role in ceramide metabolism and cell fate ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.27 Homo sapiens O95470
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.27 additional information role in ceramide metabolism and cell fate Homo sapiens ?
-
 ?
4.1.2.27 sphingosine 1-phosphate
-
 Homo sapiens phosphoethanolamine + palmitaldehyde
-
 ir

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.2.27 37
-
 assay at Homo sapiens