EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.24.B15 | functional in vitro expression by a reticulocyte lysate expression system, protein expressed in COS-7 cells is not functional | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.24.B15 | EDTA | - |
Homo sapiens | |
3.4.24.B15 | additional information | phosphoramidon is no inhibitor | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.B15 | protein + H2O | Homo sapiens | enzyme mutations are responsible for X-chromosome linked hypophosphataemia by increasing levels of circulating phosphaturic factor | peptides | - |
? | |
3.4.24.B15 | protein FGF-23 + H2O | Homo sapiens | i.e. fibroblastic growth factor 23, loss of enzyme activity results in either diminished degradation or increased biosynthesis of FGF-23 | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.B15 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.24.B15 | bone | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.B15 | additional information | recombinant protein FGF-23, i.e. fibroblastic growth factor 23 seems to be no direct substrate for the enzyme | Homo sapiens | ? | - |
? | |
3.4.24.B15 | protein + H2O | - |
Homo sapiens | peptides | - |
? | |
3.4.24.B15 | protein + H2O | enzyme mutations are responsible for X-chromosome linked hypophosphataemia by increasing levels of circulating phosphaturic factor | Homo sapiens | peptides | - |
? | |
3.4.24.B15 | protein FGF-23 + H2O | i.e. fibroblastic growth factor 23 | Homo sapiens | ? | - |
? | |
3.4.24.B15 | protein FGF-23 + H2O | i.e. fibroblastic growth factor 23, loss of enzyme activity results in either diminished degradation or increased biosynthesis of FGF-23 | Homo sapiens | ? | - |
? | |
3.4.24.B15 | Z-Ala-Ala-Leu-4-nitroanilide + H2O | chromogenic substrate | Homo sapiens | Z-Ala-Ala-Leu + 4-nitroaniline | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.24.B15 | M13.091 | Merops-ID | Homo sapiens |
3.4.24.B15 | PHEX | - |
Homo sapiens |