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Literature summary extracted from

  • Hink-Schauer, C.; Estebanez-Perpina, E.; Wilharm, E.; Fuentes-Prior, P.; Klinkert, W.; Bode, W.; Jenne, D.E.
    The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features (2002), J. Biol. Chem., 277, 50923-50933.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.B4 S195A variant expressed in Escherichia coli Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.4.21.B4 sitting drop vapor diffusion method Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
3.4.21.B4 S195A more stable but otherwise identical to wild-type enzyme Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.B4 additional information Homo sapiens can trigger DNA fragmentation and is involved in apoptosis ?
-
 ?
3.4.21.B4 Protein + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.B4 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.B4 additional information can trigger DNA fragmentation and is involved in apoptosis Homo sapiens ?
-
 ?
3.4.21.B4 Protein + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.B4 GzmK
-
 Homo sapiens