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Literature summary extracted from

  • Shin, H.S.; Chin, M.R.; Kim, J.S.; Chung, J.H.; Ryu, C.K.; Jung, S.Y.; Kim, D.K.
    Purification and characterization of a cytosolic, 42-kDa and Ca2+-dependent phospholipase A2 from bovine red blood cells: its involvement in Ca2+-dependent release of arachidonic acid from mammalian red blood cells (2002), J. Biol. Chem., 277, 21086-21094.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.4 7-chloro-6-[4-(diethylamino)phenyl]-5,8-quinolinedione competitive inhibitor Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.4 0.0139
-
 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine pH 7.5 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.4 cytosol
-
 Homo sapiens 5829
-
3.1.1.4 cytosol
-
 Bos taurus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.4 40000
-
 gel filtration Homo sapiens
3.1.1.4 42000
-
 gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.4 additional information Homo sapiens enzyme is responsible for Ca2+-dependent release of arachidonic acid from red blood cells ?
-
 ?
3.1.1.4 additional information Bos taurus enzyme is responsible for Ca2+-dependent release of arachidonic acid from red blood cells ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Bos taurus
-
-
-
3.1.1.4 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.4
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 erythrocyte
-
 Homo sapiens
-
3.1.1.4 erythrocyte
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.4 0.0056
-
-
 Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Homo sapiens 1-palmitoyl-sn-glycero-3-phosphocholine + palmitic acid
-
 ?
3.1.1.4 1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Bos taurus 1-palmitoyl-sn-glycero-3-phosphocholine + palmitic acid
-
 ?
3.1.1.4 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine + H2O
-
 Homo sapiens 1-palmitoyl-sn-glycero-3-phosphocholine + linolic acid
-
 ?
3.1.1.4 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine + H2O
-
 Bos taurus 1-palmitoyl-sn-glycero-3-phosphocholine + linolic acid
-
 ?
3.1.1.4 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine + H2O preferred substrate Homo sapiens 1-stearoyl-sn-glycero-3-phosphocholine + arachidonic acid
-
 ?
3.1.1.4 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine + H2O preferred substrate Bos taurus 1-stearoyl-sn-glycero-3-phosphocholine + arachidonic acid
-
 ?
3.1.1.4 additional information enzyme is responsible for Ca2+-dependent release of arachidonic acid from red blood cells Homo sapiens ?
-
 ?
3.1.1.4 additional information enzyme is responsible for Ca2+-dependent release of arachidonic acid from red blood cells Bos taurus ?
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.1.1.4 0.13
-
 7-chloro-6-[4-(diethylamino)phenyl]-5,8-quinolinedione pH 7.5 Bos taurus

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.1.1.4 Bos taurus isoelectric focusing
-
 3.9