BRENDA - Enzyme Database

A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein, p125

Nakajima, K.; Sonoda, H.; Mizoguchi, T.; Aoki, J.; Arai, H.; Nagahama, M.; Tagaya, M.; Tani, K.; J. Biol. Chem. 277, 11329-11335 (2002)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
3.1.1.32
cloning of cDNA, transient expression in 293 T cells
Homo sapiens
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.1.32
cytosol
predominantly
Homo sapiens
5829
-
3.1.1.32
microsome
-
Homo sapiens
-
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.1.1.32
90000
-
x * 90000, SDS-PAGE, immunoblot
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.1.32
phosphatidic acid + H2O
Homo sapiens
-
2-acyl-lysophosphatidic acid + a carboxylate
-
Homo sapiens
?
3.1.1.32
phosphatidylcholine + H2O
Homo sapiens
-
2-acylglycerophosphocholine + a carboxylate
-
Homo sapiens
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.1.32
Homo sapiens
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.32
brain
northern analysis
Homo sapiens
-
3.1.1.32
heart
northern analysis
Homo sapiens
-
3.1.1.32
kidney
northern analysis
Homo sapiens
-
3.1.1.32
liver
northern analysis
Homo sapiens
-
3.1.1.32
lung
northern analysis
Homo sapiens
-
3.1.1.32
pancreas
northern analysis
Homo sapiens
-
3.1.1.32
placenta
northern analysis
Homo sapiens
-
3.1.1.32
skeletal muscle
northern analysis
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.1.32
phosphatidic acid + H2O
-
652226
Homo sapiens
2-acyl-lysophosphatidic acid + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidic acid + H2O
best substrate
652226
Homo sapiens
2-acyl-lysophosphatidic acid + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidylcholine + H2O
-
652226
Homo sapiens
2-acylglycerophosphocholine + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidylcholine + H2O
very low activity
652226
Homo sapiens
2-acylglycerophosphocholine + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidylethanolamine + H2O
similar activity as with phosphatidic acid
652226
Homo sapiens
2-acylglycerophosphoethanolamine + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidylserine + H2O
low activity
652226
Homo sapiens
2-acylglycerophosphoserine + a carboxylate
-
652226
Homo sapiens
?
Subunits
EC Number
Subunits
Commentary
Organism
3.1.1.32
?
x * 90000, SDS-PAGE, immunoblot
Homo sapiens
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
3.1.1.32
cloning of cDNA, transient expression in 293 T cells
Homo sapiens
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
3.1.1.32
cytosol
predominantly
Homo sapiens
5829
-
3.1.1.32
microsome
-
Homo sapiens
-
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.1.1.32
90000
-
x * 90000, SDS-PAGE, immunoblot
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.1.32
phosphatidic acid + H2O
Homo sapiens
-
2-acyl-lysophosphatidic acid + a carboxylate
-
Homo sapiens
?
3.1.1.32
phosphatidylcholine + H2O
Homo sapiens
-
2-acylglycerophosphocholine + a carboxylate
-
Homo sapiens
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.32
brain
northern analysis
Homo sapiens
-
3.1.1.32
heart
northern analysis
Homo sapiens
-
3.1.1.32
kidney
northern analysis
Homo sapiens
-
3.1.1.32
liver
northern analysis
Homo sapiens
-
3.1.1.32
lung
northern analysis
Homo sapiens
-
3.1.1.32
pancreas
northern analysis
Homo sapiens
-
3.1.1.32
placenta
northern analysis
Homo sapiens
-
3.1.1.32
skeletal muscle
northern analysis
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.1.32
phosphatidic acid + H2O
-
652226
Homo sapiens
2-acyl-lysophosphatidic acid + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidic acid + H2O
best substrate
652226
Homo sapiens
2-acyl-lysophosphatidic acid + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidylcholine + H2O
-
652226
Homo sapiens
2-acylglycerophosphocholine + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidylcholine + H2O
very low activity
652226
Homo sapiens
2-acylglycerophosphocholine + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidylethanolamine + H2O
similar activity as with phosphatidic acid
652226
Homo sapiens
2-acylglycerophosphoethanolamine + a carboxylate
-
652226
Homo sapiens
?
3.1.1.32
phosphatidylserine + H2O
low activity
652226
Homo sapiens
2-acylglycerophosphoserine + a carboxylate
-
652226
Homo sapiens
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
3.1.1.32
?
x * 90000, SDS-PAGE, immunoblot
Homo sapiens