EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.24.B4 | extracellular | secretion | Rattus norvegicus | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.24.B4 | additional information | Ca2+-dependent binding to the specific receptor of osteoblastic and fibroblastic cell lines via residue I125 | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.B4 | additional information | Rattus norvegicus | osteoblastic osteosarcoma cell line UMR 106-01, Ca2+-dependent binding in a two-step mechanism via the required specific 170 kDa enzyme receptor and the required 600 kDa LDL-receptor, internalization and degradation of the enzyme, modeling, the enzyme also binds to mouse fibroblastic cells | ? | - |
? | |
3.4.24.B4 | protein + H2O | Rattus norvegicus | - |
peptides | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.B4 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.24.B4 | purification of the secreted enzyme from the cell culture medium | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.24.B4 | cell culture | uterine smooth muscle cells | Rattus norvegicus | - |
3.4.24.B4 | additional information | osteoblastic osteosarcoma cell line UMR 106-01, Ca2+-dependent binding in a two-step mechanism via the required specific enzyme receptor and LDL-receptor-related protein, internalization and degradation of the enzyme, also binding to fibroblastic cells | Rattus norvegicus | - |
3.4.24.B4 | smooth muscle | - |
Rattus norvegicus | - |
3.4.24.B4 | uterus | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.B4 | additional information | osteoblastic osteosarcoma cell line UMR 106-01, Ca2+-dependent binding in a two-step mechanism via the required specific 170 kDa enzyme receptor and the required 600 kDa LDL-receptor, internalization and degradation of the enzyme, modeling, the enzyme also binds to mouse fibroblastic cells | Rattus norvegicus | ? | - |
? | |
3.4.24.B4 | protein + H2O | - |
Rattus norvegicus | peptides | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.24.B4 | M10.013 | Merops-ID | Rattus norvegicus |
3.4.24.B4 | matrix metalloproteinase-13 | - |
Rattus norvegicus |
3.4.24.B4 | MMP-13 | - |
Rattus norvegicus |