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Literature summary extracted from

  • Skorko-Glonek, J.; Lipinska, B.; Krzewski, K.; Zolese, G.; Bertoli, E.; Tanfani, F.
    HtrA heat shock protease interacts with phospholipid membranes and undergoes conformational changes (1997), J. Biol. Chem., 272, 8974-8982.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.21.107 phosphatidylglycerol activates at 37-45°C Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.107 cardiolipin
-
 Escherichia coli
3.4.21.107 phosphatidylglycerol inhibits activity at 50-55°C Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.107 additional information Escherichia coli involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at temperatures above 42°C ?
-
 ?
3.4.21.107 Protein + H2O Escherichia coli
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.107 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.107 beta-casein + H2O
-
 Escherichia coli ?
-
 ?
3.4.21.107 additional information involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at temperatures above 42°C Escherichia coli ?
-
 ?
3.4.21.107 Protein + H2O
-
 Escherichia coli ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.107 HtrA
-
 Escherichia coli

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.21.107 additional information
-
 interaction with phosphatidylgycerol leads to a remarkable decrease in the thermal stability Escherichia coli