EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.21.B27 | wild-type and truncated form | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.B27 | CuSO4 | 97% inhibition at 1 mM | Rattus norvegicus | |
3.4.21.B27 | EDTA | 95% inhibition at 10 mM | Rattus norvegicus | |
3.4.21.B27 | ZnSO4 | 94% inhibition at 1 mM | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.B27 | 0.164 | - |
pERTKR-4-methylcoumarin 7-amide | pH 6.5 | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.21.B27 | endoplasmic reticulum | - |
Rattus norvegicus | 5783 | - |
3.4.21.B27 | membrane | mature enzyme | Rattus norvegicus | 16020 | - |
3.4.21.B27 | soluble | truncated enzyme | Rattus norvegicus | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.B27 | Ca2+ | dependent, optimal concentration: 1 mM | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.21.B27 | 65000 | - |
SDS-PAGE, truncated enzyme | Rattus norvegicus |
3.4.21.B27 | 89000 | - |
SDS-PAGE, mature enzyme | Rattus norvegicus |
3.4.21.B27 | 101000 | - |
SDS-PAGE, zymogen | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.B27 | Rattus norvegicus | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.4.21.B27 | glycoprotein | zymogen is N-glycosylated | Rattus norvegicus |
3.4.21.B27 | proteolytic modification | zymogen is processed to mature enzyme in the endoplasmic reticulum | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.B27 | KEKR-4-methylcoumarin 7-amide + H2O | weak substrate | Rattus norvegicus | KEKR + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.B27 | pERTKR-4-methylcoumarin 7-amide + H2O | - |
Rattus norvegicus | pERTKR + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.B27 | pro-parathyroid hormone tridecapeptide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.4.21.B27 | pro-PC4 heptadecapeptide + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.4.21.B27 | RFAR-4-methylcoumarin 7-amide + H2O | weak substrate | Rattus norvegicus | RFAR + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.B27 | RKKR-4-methylcoumarin 7-amide + H2O | - |
Rattus norvegicus | RKKR + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.B27 | RSKR-4-methylcoumarin 7-amide + H2O | - |
Rattus norvegicus | RSKR + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.B27 | RSKR-4-methylcoumarin 7-amide + H2O | weak substrate | Rattus norvegicus | RSKR + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.B27 | RVRR-4-methylcoumarin 7-amide + H2O | weak substrate | Rattus norvegicus | RVRR + 7-amino-4-methylcoumarin | - |
? | |
3.4.21.B27 | YEKERSKR-4-methylcoumarin 7-amide + H2O | - |
Rattus norvegicus | YEKERSKR + 7-amino-4-methylcoumarin | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.B27 | rPC7 | - |
Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.21.B27 | 6 | 7 | - |
Rattus norvegicus |