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Literature summary extracted from

  • Lee, Y.S.; Cho, Y.D.
    Comparison of biochemical and immunological properties between rat and Nicotiana glutinosa ornithine decarboxylase (2001), J. Biochem. Mol. Biol., 34, 408-414.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.17 spermidine 1 mM, 211% activation Nicotiana glutinosa
4.1.1.17 spermine 1 mM, 309% activation Nicotiana glutinosa

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.17 expression in Escherichia coli Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.17 4-chloromercuribenzoate 0.01 mM, complete inhibition Nicotiana glutinosa
4.1.1.17 4-chloromercuribenzoate 0.01 mM, 99% inhibition Rattus norvegicus
4.1.1.17 5,5'-dithiobis(2-nitrobenzoic acid) 0.01 mM, 99% inhibition Nicotiana glutinosa
4.1.1.17 5,5'-dithiobis(2-nitrobenzoic acid) 0.01 mM, 98% inhibition Rattus norvegicus
4.1.1.17 agmatine 1 mM, 77% inhibition Nicotiana glutinosa
4.1.1.17 cadaverine 1 mM, 46% inhibition Nicotiana glutinosa
4.1.1.17 ethyl[dimethylaminopropyl]carbodiimide 1.0 mM, 54% inhibition Nicotiana glutinosa
4.1.1.17 ethyl[dimethylaminopropyl]carbodiimide 1.0 mM, 52% inhibition Rattus norvegicus
4.1.1.17 MTA 1 mM, 70% inhibition Rattus norvegicus
4.1.1.17 N-ethylmaleimide 0.01 mM, complete inhibition Nicotiana glutinosa
4.1.1.17 N-ethylmaleimide 0.01 mM, 99% inhibition Rattus norvegicus
4.1.1.17 Phenylglyoxal 1.0 mM, 36% inhibition Nicotiana glutinosa
4.1.1.17 Phenylglyoxal 1.0 mM, 71% inhibition Rattus norvegicus
4.1.1.17 putrescine 1 mM, 70% inhibition Nicotiana glutinosa
4.1.1.17 putrescine 1 mM, 63% inhibition Rattus norvegicus
4.1.1.17 Salicylaldehyde 1.0 mM, 98% inhibition Nicotiana glutinosa
4.1.1.17 Salicylaldehyde 1.0 mM, 82% inhibition Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.17 46000
-
 2 * 46000, SDS-PAGE Nicotiana glutinosa
4.1.1.17 53000
-
 2 * 53000, SDS-PAGE Rattus norvegicus
4.1.1.17 92000
-
 native PAGE Nicotiana glutinosa
4.1.1.17 106000
-
 native PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.17 L-ornithine Nicotiana glutinosa
-
 putrescine + CO2
-
 ?
4.1.1.17 L-ornithine Rattus norvegicus
-
 putrescine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.17 Nicotiana glutinosa Q9FPK5
-
-
4.1.1.17 Rattus norvegicus P09057
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.17 recombinant ODC Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.17 L-ornithine
-
 Nicotiana glutinosa putrescine + CO2
-
 ?
4.1.1.17 L-ornithine
-
 Rattus norvegicus putrescine + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.17 dimer 2 * 53000, SDS-PAGE Rattus norvegicus
4.1.1.17 dimer 2 * 46000, SDS-PAGE Nicotiana glutinosa

Synonyms

EC Number Synonyms Comment Organism
4.1.1.17 ODC
-
 Nicotiana glutinosa
4.1.1.17 ODC
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.17 pyridoxal 5'-phosphate
-
 Nicotiana glutinosa
4.1.1.17 pyridoxal 5'-phosphate
-
 Rattus norvegicus