Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Skorko-Glonek, J.; Wawrzynow, A.; Krzewski, K.; Kurpierz, K.; Lipinska, B.
    Site-directed mutagenesis of the HtrA (DegP) serine protease, whose proteolytic activity is indispensable for Escherichia coli survival at elevated temperatures (1995), Gene, 163, 47-52.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.107
-
 Escherichia coli

Protein Variants

EC Number Protein Variants Comment Organism
3.4.21.107 H105R loss of protease activity, no change in secondary structure Escherichia coli
3.4.21.107 S210A loss of protease activity, no change in secondary structure Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.107 51000
-
 precursor protein, SDS-PAGE Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.107 additional information Escherichia coli involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at elevated temperatures ?
-
 ?
3.4.21.107 Protein + H2O Escherichia coli
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.107 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.107 wild-type, S210A and H105R mutant Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.107 beta-casein + H2O
-
 Escherichia coli ?
-
 ?
3.4.21.107 additional information involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at elevated temperatures Escherichia coli ?
-
 ?
3.4.21.107 Protein + H2O
-
 Escherichia coli ?
-
 ?