EC Number | Cloned (Comment) | Organism |
---|---|---|
5.1.1.1 | amplified by PCR, cloned and overexpressed in Escherichia coli BL21, both as native and His-tagged products | Mycobacterium avium |
5.1.1.1 | amplified by PCR, cloned and overexpressed in Escherichia coli BL21, both as native and His-tagged products | Mycobacterium tuberculosis |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
5.1.1.1 | cycloserine | D-cycloserine or a racemic mixture of D- and L-cycloserine | Mycobacterium avium | |
5.1.1.1 | cycloserine | D-cycloserine or a racemic mixture of D- and L-cycloserine | Mycobacterium tuberculosis |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
5.1.1.1 | 0.4 | - |
D-Ala | - |
Mycobacterium avium | |
5.1.1.1 | 0.5 | - |
L-Ala | - |
Mycobacterium avium | |
5.1.1.1 | 1.1 | - |
D-Ala | 23°C | Mycobacterium tuberculosis | |
5.1.1.1 | 1.2 | - |
L-Ala | 23°C | Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.1.1.1 | Mycobacterium avium | - |
- |
- |
5.1.1.1 | Mycobacterium tuberculosis | P9WQA9 | - |
- |
5.1.1.1 | Mycobacterium tuberculosis H37Rv | P9WQA9 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
5.1.1.1 | - |
Mycobacterium avium |
5.1.1.1 | - |
Mycobacterium tuberculosis |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.1.1.1 | L-Ala | - |
Mycobacterium avium | D-Ala | - |
r | |
5.1.1.1 | L-Ala | - |
Mycobacterium tuberculosis | D-Ala | - |
r | |
5.1.1.1 | L-Ala | - |
Mycobacterium tuberculosis H37Rv | D-Ala | - |
r |