Literature summary extracted from

Saario, S.M.; Savinainen, J.R.; Laitinen, J.T.; Jarvinen, T.; Niemi, R.
Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes (2004), Biochem. Pharmacol., 67, 1381-1387.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.1.23	arachidonoyl trifluoromethylketone	50% inhibition at 0.066 mM	Rattus norvegicus
3.1.1.23	hexadecylsufonyl fluoride	50% inhibition at 0.000241 mM	Rattus norvegicus
3.1.1.23	methyl arachidonyl fluorophosphonate	50% inhibition at 0.0000022 mM	Rattus norvegicus
3.1.1.23	phenylmethylsulfonyl fluoride	50% inhibition at 0.155 mM	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.1.1.23	membrane	-	Rattus norvegicus	16020	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.1.23	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.1.23	brain	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
3.1.1.23	0.0298	-	with 1(3)-arachidonoylglycerol as substrate	Rattus norvegicus
3.1.1.23	0.0318	-	with 2-arachidonoylglycerol as substrate	Rattus norvegicus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.1.23	1(3)-arachidonoylglycerol + H2O	-	Rattus norvegicus	? + glycerol	-	?
3.1.1.23	2-arachidonoylglycerol + H2O	-	Rattus norvegicus	arachidonic acid + glycerol	-	?

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Release 2023.1 (January 2023)