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Literature summary extracted from

  • Benedetti, A.; Fulceri, R.; Allan, B.B.; Houston, P.; Sukhodub, A.L.; Marcolongo, P.; Ethell, B.; Burchell, B.; Burchell, A.
    Histone 2A stimulates glucose-6-phosphatase activity by permeabilization of liver microsomes (2002), Biochem. J., 367, 505-510.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.9 alamethicin
-
 Rattus norvegicus
3.1.3.9 deoxycholate
-
 Rattus norvegicus
3.1.3.9 HECAMEG
-
 Rattus norvegicus
3.1.3.9 Histone 2A stimulates enzyme activity by permeabilizing the microsomal membrane Rattus norvegicus
3.1.3.9 Lubrol
-
 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.9 EGTA inhibits enzyme activity in histone 2A-treated or alamethicin-treated microsomes, but has little effect on enzyme activity in intact microsomes Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.9 microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.9 D-glucose 6-phosphate + H2O Rattus norvegicus the enzyme catalyses the terminal reaction of gluconegenesis and glycogenolysis and plays a major role in the contol of blood glucose levels D-glucose + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.9 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.9 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.9 D-glucose 6-phosphate + H2O
-
 Rattus norvegicus D-glucose + phosphate
-
 ?
3.1.3.9 D-glucose 6-phosphate + H2O the enzyme catalyses the terminal reaction of gluconegenesis and glycogenolysis and plays a major role in the contol of blood glucose levels Rattus norvegicus D-glucose + phosphate
-
 ?