EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.32 | Triton X-100 | 1%, 12.4fold increase in activity | Trypanosoma cruzi |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.32 | chlorpromazine | 1 mM, 50% inhibition | Trypanosoma cruzi |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.1.32 | lysosome | - |
Trypanosoma cruzi | 5764 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.1.32 | 38000 | - |
1 * 38000, SDS-PAGE | Trypanosoma cruzi |
3.1.1.32 | 40000 | - |
gel filtration | Trypanosoma cruzi |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.32 | 1-palmitoyl-2-oleoyl-phosphatidylcholine + H2O | Trypanosoma cruzi | - |
2-oleoyl-lysophosphatidylcholine + palmitic acid | - |
? | |
3.1.1.32 | phosphatidylcholine + H2O | Trypanosoma cruzi | - |
2-acylglycerophosphocholine + a carboxylate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.32 | Trypanosoma cruzi | - |
Plase A1 may play a role in the pathogenesis of Chagas' disease | - |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.1.1.32 | glycoprotein | indicated by binding to ConA-Sepharose | Trypanosoma cruzi |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.1.32 | purified from epimastogote homogenate supernatants, DEAE-Trisacryl, ConA-Sepharose 4B, CM-Sepharose | Trypanosoma cruzi |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.1.1.32 | 0.35 | - |
- |
Trypanosoma cruzi |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.32 | 1-palmitoyl-2-oleoyl-phosphatidylcholine + H2O | - |
Trypanosoma cruzi | 2-oleoyl-lysophosphatidylcholine + palmitic acid | - |
? | |
3.1.1.32 | phosphatidylcholine + H2O | - |
Trypanosoma cruzi | 2-acylglycerophosphocholine + a carboxylate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.1.32 | monomer | 1 * 38000, SDS-PAGE | Trypanosoma cruzi |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.1.32 | Plase A1 | - |
Trypanosoma cruzi |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.1.32 | 4 | 5 | - |
Trypanosoma cruzi |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.1.1.32 | 3 | 7 | approx. 50% of maximal activity at pH 3.0, approx. 20% of maximal activity at pH 6.0 | Trypanosoma cruzi |