EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.2 | CTP | IC50: 0.32 mM | Saccharomyces cerevisiae |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
6.3.4.2 | Mg2+ | dUTP-dependent activity is dependent on Mg2+, maximal activity at 4 mM | Saccharomyces cerevisiae |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.4.2 | Saccharomyces cerevisiae | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.3.4.2 | - |
Saccharomyces cerevisiae |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
6.3.4.2 | 1.3 | - |
- |
Saccharomyces cerevisiae |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.4.2 | ATP + dUTP + NH4+ | - |
Saccharomyces cerevisiae | ADP + phosphate + dCTP | - |
? | |
6.3.4.2 | ATP + UTP + NH4+ | - |
Saccharomyces cerevisiae | ADP + phosphate + CTP | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
6.3.4.2 | tetramer | UTP and ATP are responsible for the tetramerization and activation of the inactive dimeric form of the enzyme. UTP is absolutely required for the tatramerization of the enzyme when ATP is present at a saturating concentration | Saccharomyces cerevisiae |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.3.4.2 | 8 | - |
dUTP-dependent activity | Saccharomyces cerevisiae |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
6.3.4.2 | 7.5 | 9 | pH 7.5: about 70% of maximal activity, pH 9.0: about 55% of maximal activity, dUTP-dependent activity | Saccharomyces cerevisiae |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
6.3.4.2 | 0.32 | - |
IC50: 0.32 mM | Saccharomyces cerevisiae | CTP |