EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.4.1.16 | alpha-Keto acids | restore activity during reaction | Sus scrofa |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.4.1.16 | L-cysteine | competitive | Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.4.1.16 | 0.52 | - |
L-selenocysteine | pH 8.5 | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.4.1.16 | L-selenocysteine + reduced acceptor | Sus scrofa | - |
selenide + L-alanine + acceptor | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.4.1.16 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.4.1.16 | - |
Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.4.1.16 | liver | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.4.1.16 | L-selenocysteine + reduced acceptor | - |
Sus scrofa | selenide + L-alanine + acceptor | - |
? | |
4.4.1.16 | L-selenocysteine + reduced acceptor | enzyme bound pyridoxal 5'-phosphate serves as acceptor | Sus scrofa | selenide + L-alanine + acceptor | enzyme bound pyridoxamine 5'-phosphate formed during reaction, regeneration of enzyme by addition of an alpha-keto acid | ? | |
4.4.1.16 | L-selenocysteine + reduced acceptor | enzyme bound pyridoxal 5'-phosphate serves as acceptor | Sus scrofa | selenide + L-alanine + acceptor | formation of H2Se by nonenzymatic reduction of elemental selenium in presence of dithiothreitol | ? | |
4.4.1.16 | L-selenocysteine + reduced acceptor | enzyme is inativated during course of reaction without addition of pyridoxal 5'-phosphate | Sus scrofa | selenide + L-alanine + acceptor | enzyme bound pyridoxamine 5'-phosphate formed during reaction, regeneration of enzyme by addition of an alpha-keto acid | ? | |
4.4.1.16 | L-selenocysteine + reduced acceptor | enzyme is inativated during course of reaction without addition of pyridoxal 5'-phosphate | Sus scrofa | selenide + L-alanine + acceptor | formation of H2Se by nonenzymatic reduction of elemental selenium in presence of dithiothreitol | ? | |
4.4.1.16 | additional information | no activity with L-cysteine | Sus scrofa | ? | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
4.4.1.16 | pyridoxal 5'-phosphate | required | Sus scrofa |