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Literature summary extracted from
- Lysosomal sequestration of cytosolic enzymes and lysosomal thiol cathepsins (1985), Adv. Enzyme Regul., 23, 159-168.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.15 | leupeptin | - |
Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.15 | additional information | Rattus norvegicus | the enzyme plays a most important role in intralysosomal proteolysis in hepatocytes | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.15 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.22.15 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.22.15 | liver | only in hepatocytes | Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.15 | additional information | the enzyme plays a most important role in intralysosomal proteolysis in hepatocytes | Rattus norvegicus | ? | - |
? | |
| 3.4.22.15 | succinyl-Tyr-Met-2-naphthylamide + H2O | - |
Rattus norvegicus | ? | - |
? | |
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Release 2023.1 (January 2023)
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