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Literature summary extracted from
- Idenification, purification, and localization of tissue kallikrein in rat heart (1990), Biochem. J., 267, 639-646.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.35 | Lima-bean trypsin inhibitor | stimulates | Rattus norvegicus | |
| 3.4.21.35 | ovomucoid trypsin inhibitor | stimulates | Rattus norvegicus | |
| 3.4.21.35 | Soybean trypsin inhibitor | at low concentrations | Rattus norvegicus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.35 | antipain | - |
Rattus norvegicus |  |
| 3.4.21.35 | Aprotinin | - |
Rattus norvegicus | |
| 3.4.21.35 | leupeptin | - |
Rattus norvegicus | |
| 3.4.21.35 | Soybean trypsin inhibitor | at high concentrations | Rattus norvegicus |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.21.35 | sarcoplasmic reticulum | - |
Rattus norvegicus | 16529 | - |
| 3.4.21.35 | specific granule | granules of rat atrial myocytes | Rattus norvegicus | 42581 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.35 | polypeptide + H2O | Rattus norvegicus | - |
peptides | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.35 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.21.35 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.35 | atrium | - |
Rattus norvegicus | - |
| 3.4.21.35 | heart | - |
Rattus norvegicus | - |
| 3.4.21.35 | myocyte | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.35 | kininogen + H2O | - |
Rattus norvegicus | kinin + ? | - |
? | |
| 3.4.21.35 | low-molecular-weight kininogen + H2O | - |
Rattus norvegicus | kallidin + kinin | - |
? | |
| 3.4.21.35 | polypeptide + H2O | - |
Rattus norvegicus | peptides | - |
? | |
| 3.4.21.35 | Tosyl-Arg methyl ester + H2O | - |
Rattus norvegicus | Tosyl-Arg + methanol | - |
? | |
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