Any feedback?
Literature summary extracted from
- Folate conjugase: two separate activities in human jejunum (1977), Science, 198, 196-197.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.19.9 | p-hydroxymercuribenzoate | soluble intracellular enzyme is inhibited, membrane-bound brush-border enzyme not | Homo sapiens |  |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.19.9 | soluble | intracellular | Homo sapiens | - |
- |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.19.9 | 45000 | - |
soluble intracellular enzyme, gel filtration | Homo sapiens |
| 3.4.19.9 | 91000 | - |
membrane-bound enzyme, gel filtration | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.19.9 | pteroylpolyglutamate + H2O | Homo sapiens | folate conjugase in the brush-border may accomplish the initial digestion of the dietary pteroylpolyglutamates | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.19.9 | Homo sapiens | - |
two separate folate conjugase activities in jejunal mucosa: one membrane-bound and concentrated in the brush-border and the other soluble and intracellular | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.19.9 | jejunum | mucosal brush-border | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.19.9 | additional information | soluble enzyme has a requirement for sulfhydryl groups in the active site | Homo sapiens | ? | - |
? | |
| 3.4.19.9 | pteroylpolyglutamate + H2O | folate conjugase in the brush-border may accomplish the initial digestion of the dietary pteroylpolyglutamates | Homo sapiens | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.19.9 | 4.5 | - |
soluble intracellular enzyme | Homo sapiens |
| 3.4.19.9 | 7.5 | - |
brush-border enzyme | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
