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Literature summary extracted from

  • Bauer, K.; Nowak, P.; Kleinkauf, H.
    Specificity of a serum peptidase hydrolyzing thyroliberin at pyroglutamyl-histidine bone (1981), Eur. J. Biochem., 118, 173-176.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.19.6 Luliberin
-
 Sus scrofa
3.4.19.6 neurotensin
-
 Sus scrofa
3.4.19.6 Thyroliberin analogues LLD-thyroliberin, pyroglutamyl-His-Pro-NHCH3, pyroglutamyl-His-Pro-Gly-NHCH3, pyroglutamyl-Phe-Pro-NH2 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.19.6 0.056
-
 Thyroliberin
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.19.6 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.19.6 serum
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.19.6 additional information no hydrolysis of pyroglutamyl-His Sus scrofa ?
-
 ?
3.4.19.6 additional information no hydrolysis of pyroglutamyl-Ala or pyroglutamyl 2-naphthylamide (known substrates of the serum enzyme) Sus scrofa ?
-
 ?
3.4.19.6 additional information no hydrolysis of neurotensin Sus scrofa ?
-
 ?
3.4.19.6 additional information no hydrolysis of thyroliberin analogues LLD-thyroliberin, pyroglutamyl-His-Pro-NHCH3, pyroglutamyl-His-Pro-Gly-NHCH3 or pyroglutamyl-Phe-Pro-NH2 Sus scrofa ?
-
 ?
3.4.19.6 additional information no hydrolysis of luliberin Sus scrofa ?
-
 ?
3.4.19.6 thyroliberin + H2O rapid stereospecific cleavage only of the pyroglutamyl-histidine bond of thyroliberin and closely related peptides Sus scrofa pyroglutamic acid + His-Pro-NH2
-
 ?