Any feedback?
Literature summary extracted from
- Leukotriene A4 hydrolase from guinea pig lung: the presence of two catalytically active forms (1989), J. Biochem., 105, 261-264.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.3.2.6 | medicine | the enzyme catalyses the hydrolysis of leukotriene A4 into the proinflammatory substance leukotriene B4 | Cavia porcellus |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.3.2.6 | 0.017 | - |
leukotriene A4 | pH 7.8, 37°C | Cavia porcellus |  |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.3.2.6 | 45000 | - |
gel filtration | Cavia porcellus |
| 3.3.2.6 | 70000 | - |
x * 70000, SDS-PAGE | Cavia porcellus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.3.2.6 | Cavia porcellus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.3.2.6 | - |
Cavia porcellus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.3.2.6 | lung | - |
Cavia porcellus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.3.2.6 | 0.53 | - |
- |
Cavia porcellus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.3.2.6 | leukotriene A4 + H2O | - |
Cavia porcellus | leukotriene B4 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.3.2.6 | ? | x * 70000, SDS-PAGE | Cavia porcellus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.3.2.6 | 7.6 | 8.9 | - |
Cavia porcellus |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 3.3.2.6 | Cavia porcellus | chromatofocusing, isoelectric focusing, in absence of SH reducing reagents | - |
5.4 |
| 3.3.2.6 | Cavia porcellus | chromatofocusing, isoelectric focusing, in presence of SH reducing reagents | - |
5.7 |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
