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Literature summary extracted from

  • Roth, J.; Ziak, M.; Zuber, C.
    The role of glucosidase II and endomannosidase in glucose trimming of asparagine-linked oligosaccharides (2003), Biochimie, 85, 287-294.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.130 additional information unaffected by glucosidase inhibitors Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.130 endoplasmic reticulum
-
 Rattus norvegicus 5783
-
3.2.1.130 Golgi apparatus
-
 Rattus norvegicus 5794
-
3.2.1.130 Golgi apparatus pre-Golgi intermediate Rattus norvegicus 5794
-
3.2.1.130 Golgi membrane
-
 Rattus norvegicus 139
-
3.2.1.207 endoplasmic reticulum
-
 Sus scrofa 5783
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.207 11000
-
 alpha, beta, 1 * 11000 + 1 * 80000, catalytic alpha subunit and beta subunit of unknown function Sus scrofa
3.2.1.207 80000
-
 alpha, beta, 1 * 11000 + 1 * 80000, catalytic alpha subunit and beta subunit of unknown function Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.130 GlcMan9GlcNAc + H2O Rattus norvegicus glucose trimming of asparagine-linked oligosaccharides Man8GlcNAc + glucosyl alpha1,3-mannose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O Drosophila melanogaster
-
 Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O Mus musculus
-
 Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O Homo sapiens
-
 Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O Rattus norvegicus
-
 Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O Sus scrofa
-
 Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O Saccharomyces cerevisiae
-
 Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O Bos taurus
-
 Man9GlcNAc2 + alpha-D-glucose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.130 Rattus norvegicus
-
-
-
3.2.1.207 Bos taurus
-
 two isoforms derived by alternative spicing, isofoms 2 contains a 22 amino acid insert
-
3.2.1.207 Drosophila melanogaster
-
 one isoform
-
3.2.1.207 Homo sapiens
-
 two isoforms derived by alternative spicing, isofoms 2 contains a 22 amino acid insert
-
3.2.1.207 Mus musculus
-
 two isoforms derived by alternative spicing, isofoms 2 contains a 22 amino acid insert
-
3.2.1.207 Rattus norvegicus
-
 two isoforms derived by alternative spicing, isofoms 2 contains a 22 amino acid insert
-
3.2.1.207 Saccharomyces cerevisiae
-
 one isoform
-
3.2.1.207 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.207 kidney embryonic and adult cells Rattus norvegicus
-
3.2.1.207 liver
-
 Rattus norvegicus
-
3.2.1.207 liver
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.130 Glc3Man9GlcNAc2 + H2O
-
 Rattus norvegicus ?
-
 ?
3.2.1.130 GlcMan9GlcNAc + H2O
-
 Rattus norvegicus Man8GlcNAc + glucosyl alpha1,3-mannose
-
 ?
3.2.1.130 GlcMan9GlcNAc + H2O glucose trimming of asparagine-linked oligosaccharides Rattus norvegicus Man8GlcNAc + glucosyl alpha1,3-mannose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O
-
 Drosophila melanogaster Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O
-
 Mus musculus Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O
-
 Homo sapiens Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O
-
 Rattus norvegicus Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O
-
 Sus scrofa Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O
-
 Saccharomyces cerevisiae Man9GlcNAc2 + alpha-D-glucose
-
 ?
3.2.1.207 Glc2Man9GlcNAc2 + H2O
-
 Bos taurus Man9GlcNAc2 + alpha-D-glucose
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.1.207 dimer alpha, beta, 1 * 11000 + 1 * 80000, catalytic alpha subunit and beta subunit of unknown function Sus scrofa