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Literature summary extracted from

  • Doorn, J.A.; Sorenson, R.C.; Billecke, S.S.; Hsu, C.; La Du, B.N.
    Evidence that several conserved histidine residues are required for hydrolytic activity of human paraoxonase/arylesterase (1999), Chem. Biol. Interact., 119-120, 235-241.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
3.1.8.1 H114N catalytically inactive Homo sapiens
3.1.8.1 H133N catalytically inactive Homo sapiens
3.1.8.1 H284N catalytically inactive Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.8.1 diethyldicarbonate
-
Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.8.1 Homo sapiens
-
PON1 type Q
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.1.8.1 an aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol mechanism Homo sapiens