Literature summary extracted from
Doorn, J.A.; Sorenson, R.C.; Billecke, S.S.; Hsu, C.; La Du, B.N.
Evidence that several conserved histidine residues are required for hydrolytic activity of human paraoxonase/arylesterase (1999), Chem. Biol. Interact., 119-120, 235-241.
Protein Variants
EC Number |
Protein Variants |
Comment |
Organism |
---|
3.1.8.1 |
H114N |
catalytically inactive |
Homo sapiens |
3.1.8.1 |
H133N |
catalytically inactive |
Homo sapiens |
3.1.8.1 |
H284N |
catalytically inactive |
Homo sapiens |
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
3.1.8.1 |
diethyldicarbonate |
- |
Homo sapiens |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
3.1.8.1 |
Homo sapiens |
- |
PON1 type Q |
- |
Reaction
EC Number |
Reaction |
Comment |
Organism |
Reaction ID |
---|
3.1.8.1 |
an aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol |
mechanism |
Homo sapiens |
|