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Literature summary extracted from

  • Rhode, H.; Schulze, M.; Cumme, G.A.; Gohlert, A.; Blume, E.; Bublitz, R.; Schilling, K.; Horn, A.
    Glycosylphosphatidylinositol-specific phospholipase D of human serum--activity modulation by naturally occurring amphiphiles (2000), Biol. Chem., 381, 471-485.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.4.50 monoacylglycerol
-
 Homo sapiens
3.1.4.50 additional information effects of natural amphiphiles Homo sapiens
3.1.4.50 n-butanol about 4fold activity at 6% butanol Homo sapiens
3.1.4.50 phosphatidylethanolamine activation Homo sapiens
3.1.4.50 Triton X-100 activation, best at 1-2 mM Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.50 cholesteryl ester strong Homo sapiens
3.1.4.50 ganglioside strong Homo sapiens
3.1.4.50 additional information effects of natural amphiphiles Homo sapiens
3.1.4.50 phosphatidic acid
-
 Homo sapiens
3.1.4.50 phosphatidylglycerol strong Homo sapiens
3.1.4.50 phosphatidylinositol strong Homo sapiens
3.1.4.50 phosphatidylserine strong Homo sapiens
3.1.4.50 sphingomyelin strong Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.4.50 103000
-
 x * 103000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.50 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.4.50
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.50 serum
-
 Homo sapiens
-

Subunits

EC Number Subunits Comment Organism
3.1.4.50 ? x * 103000, SDS-PAGE Homo sapiens