BRENDA - Enzyme Database

Glycosylphosphatidylinositol-specific phospholipase D of human serum--activity modulation by naturally occurring amphiphiles

Rhode, H.; Schulze, M.; Cumme, G.A.; Gohlert, A.; Blume, E.; Bublitz, R.; Schilling, K.; Horn, A.; Biol. Chem. 381, 471-485 (2000)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.4.50
monoacylglycerol
-
Homo sapiens
3.1.4.50
additional information
effects of natural amphiphiles
Homo sapiens
3.1.4.50
n-butanol
about 4fold activity at 6% butanol
Homo sapiens
3.1.4.50
phosphatidylethanolamine
activation
Homo sapiens
3.1.4.50
Triton X-100
activation, best at 1-2 mM
Homo sapiens
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.50
cholesteryl ester
strong
Homo sapiens
3.1.4.50
ganglioside
strong
Homo sapiens
3.1.4.50
additional information
effects of natural amphiphiles
Homo sapiens
3.1.4.50
phosphatidic acid
-
Homo sapiens
3.1.4.50
phosphatidylglycerol
strong
Homo sapiens
3.1.4.50
phosphatidylinositol
strong
Homo sapiens
3.1.4.50
phosphatidylserine
strong
Homo sapiens
3.1.4.50
sphingomyelin
strong
Homo sapiens
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.1.4.50
103000
-
x * 103000, SDS-PAGE
Homo sapiens
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.4.50
Homo sapiens
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
3.1.4.50
-
Homo sapiens
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.4.50
serum
-
Homo sapiens
-
Subunits
EC Number
Subunits
Commentary
Organism
3.1.4.50
?
x * 103000, SDS-PAGE
Homo sapiens
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.4.50
monoacylglycerol
-
Homo sapiens
3.1.4.50
additional information
effects of natural amphiphiles
Homo sapiens
3.1.4.50
n-butanol
about 4fold activity at 6% butanol
Homo sapiens
3.1.4.50
phosphatidylethanolamine
activation
Homo sapiens
3.1.4.50
Triton X-100
activation, best at 1-2 mM
Homo sapiens
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.50
cholesteryl ester
strong
Homo sapiens
3.1.4.50
ganglioside
strong
Homo sapiens
3.1.4.50
additional information
effects of natural amphiphiles
Homo sapiens
3.1.4.50
phosphatidic acid
-
Homo sapiens
3.1.4.50
phosphatidylglycerol
strong
Homo sapiens
3.1.4.50
phosphatidylinositol
strong
Homo sapiens
3.1.4.50
phosphatidylserine
strong
Homo sapiens
3.1.4.50
sphingomyelin
strong
Homo sapiens
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
3.1.4.50
103000
-
x * 103000, SDS-PAGE
Homo sapiens
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
3.1.4.50
-
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.4.50
serum
-
Homo sapiens
-
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
3.1.4.50
?
x * 103000, SDS-PAGE
Homo sapiens