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Literature summary extracted from

  • Svensson, L.T.; Alexson, S.E.H.; Hiltunen, J.K.
    Very long chain and long chain acyl-CoA thioesterase in rat liver mitochondria (1995), J. Biol. Chem., 270, 12177-12183.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.2.2 Triton X-100 0.005% slightly stimulates the activity Rattus norvegicus
3.1.2.20 Triton X-100 0.005% slightly stimulates the activity Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.2.2 p-chloromercuribenzoic acid
-
 Rattus norvegicus
3.1.2.2 Triton X-100 0.05-.0025% inhibits the activity Rattus norvegicus
3.1.2.20 p-chloromercuribenzoic acid
-
 Rattus norvegicus
3.1.2.20 Triton X-100 0.05-.0025% inhibits the activity Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.2.2 cytosol
-
 Rattus norvegicus 5829
-
3.1.2.2 mitochondrion
-
 Rattus norvegicus 5739
-
3.1.2.2 peroxisome
-
 Rattus norvegicus 5777
-
3.1.2.20 cytosol
-
 Rattus norvegicus 5829
-
3.1.2.20 mitochondrion
-
 Rattus norvegicus 5739
-
3.1.2.20 peroxisome
-
 Rattus norvegicus 5777
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.2.2 40000
-
 gel filtration Rattus norvegicus
3.1.2.20 40000
-
 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.2 palmitoyl-CoA + H2O Rattus norvegicus
-
 CoA + palmitate
-
 ?
3.1.2.20 palmitoyl-CoA + H2O Rattus norvegicus
-
 CoA + palmitate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.2 Rattus norvegicus
-
-
-
3.1.2.20 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.2 liver
-
 Rattus norvegicus
-
3.1.2.20 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.2 arachidonoyl-CoA + H2O
-
 Rattus norvegicus CoA + arachidonate
-
 ?
3.1.2.2 decanoyl-CoA + H2O
-
 Rattus norvegicus CoA + decanoate
-
 ?
3.1.2.2 dodecanoyl-CoA + H2O i.e. lauroyl-CoA Rattus norvegicus CoA + dodecanoate
-
 ?
3.1.2.2 hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Rattus norvegicus CoA + hexadecanoate
-
 ?
3.1.2.2 octadecanoyl-CoA + H2O i.e. stearoyl-CoA Rattus norvegicus CoA + octadecanoate
-
 ?
3.1.2.2 octanoyl-CoA + H2O
-
 Rattus norvegicus CoA + octanoate
-
 ?
3.1.2.2 palmitoyl-CoA + H2O
-
 Rattus norvegicus CoA + palmitate
-
 ?
3.1.2.2 tetradecanoyl-CoA + H2O i.e. myristoyl-CoA Rattus norvegicus CoA + tetradecanoate
-
 ?
3.1.2.20 arachidonoyl-CoA + H2O
-
 Rattus norvegicus CoA + arachidonate
-
 ?
3.1.2.20 decanoyl-CoA + H2O
-
 Rattus norvegicus CoA + decanoate
-
 ?
3.1.2.20 dodecanoyl-CoA + H2O i.e. lauroyl-CoA Rattus norvegicus CoA + dodecanoate
-
 ?
3.1.2.20 hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Rattus norvegicus CoA + hexadecanoate
-
 ?
3.1.2.20 octadecanoyl-CoA + H2O i.e. stearoyl-CoA Rattus norvegicus CoA + octadecanoate
-
 ?
3.1.2.20 octanoyl-CoA + H2O
-
 Rattus norvegicus CoA + octanoate
-
 ?
3.1.2.20 palmitoyl-CoA + H2O
-
 Rattus norvegicus CoA + palmitate
-
 ?
3.1.2.20 tetradecanoyl-CoA + H2O i.e. myristoyl-CoA Rattus norvegicus CoA + tetradecanoate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.2.2 8 9
-
 Rattus norvegicus
3.1.2.20 8 9
-
 Rattus norvegicus