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Literature summary extracted from

  • Barnes jr., E.M.; Wakil, S.J.
    Studies on the mechanism of fatty acid synthesis. XIX. Preparation and general properties of palmityl thioesterase (1968), J. Biol. Chem., 243, 2955-2962.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.2.2 diisopropylfluorophosphate at 0.01 mM inhibition of 95% after 40 min. Escherichia coli
3.1.2.20 diisopropylfluorophosphate at 0.01 mM inhibition of 95% after 40 min. Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.2.2 20000
-
 sedimentation velocity Escherichia coli
3.1.2.20 20000
-
 sedimentation velocity Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.2 palmitoyl-CoA + H2O Escherichia coli
-
 CoA + palmitate
-
 ?
3.1.2.20 palmitoyl-CoA + H2O Escherichia coli
-
 CoA + palmitate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.2 Columba sp.
-
-
-
3.1.2.2 Escherichia coli
-
-
-
3.1.2.20 Columba sp.
-
-
-
3.1.2.20 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.2.2 260fold Escherichia coli
3.1.2.20 260fold Escherichia coli

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.2 liver
-
 Columba sp.
-
3.1.2.20 liver
-
 Columba sp.
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.2.2 3.7
-
-
 Escherichia coli
3.1.2.20 3.7
-
-
 Escherichia coli

Storage Stability

EC Number Storage Stability Organism
3.1.2.2 -20°C over 1 month Escherichia coli
3.1.2.20 -20°C over 1 month Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.2 dodecanoyl-CoA + H2O i.e. lauroyl-CoA Escherichia coli CoA + dodecanoate
-
 ?
3.1.2.2 hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Escherichia coli CoA + hexadecanoate
-
 ir
3.1.2.2 octadecanoyl-CoA + H2O i.e. stearoyl-CoA Escherichia coli CoA + octadecanoate
-
 ?
3.1.2.2 oleoyl-CoA + H2O
-
 Escherichia coli CoA + oleate
-
 ?
3.1.2.2 palmitoleoyl-CoA + H2O
-
 Escherichia coli CoA + palmitoleoate
-
 ?
3.1.2.2 palmitoyl-CoA + H2O
-
 Escherichia coli CoA + palmitate
-
 ?
3.1.2.2 tetradecanoyl-CoA + H2O i.e. myristoyl-CoA Escherichia coli CoA + tetradecanoate
-
 ?
3.1.2.2 vaccenoyl-CoA + H2O cis-isomer Escherichia coli CoA + vaccenoate
-
 ?
3.1.2.20 dodecanoyl-CoA + H2O i.e. lauroyl-CoA Escherichia coli CoA + dodecanoate
-
 ?
3.1.2.20 hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Escherichia coli CoA + hexadecanoate
-
 ir
3.1.2.20 octadecanoyl-CoA + H2O i.e. stearoyl-CoA Escherichia coli CoA + octadecanoate
-
 ?
3.1.2.20 oleoyl-CoA + H2O
-
 Escherichia coli CoA + oleate
-
 ?
3.1.2.20 palmitoleoyl-CoA + H2O
-
 Escherichia coli CoA + palmitoleoate
-
 ?
3.1.2.20 palmitoyl-CoA + H2O
-
 Escherichia coli CoA + palmitate
-
 ?
3.1.2.20 tetradecanoyl-CoA + H2O i.e. myristoyl-CoA Escherichia coli CoA + tetradecanoate
-
 ?
3.1.2.20 vaccenoyl-CoA + H2O cis-isomer Escherichia coli CoA + vaccenoate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.2.2 dimer
-
 Escherichia coli
3.1.2.20 dimer
-
 Escherichia coli