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Literature summary extracted from

  • Dupre, S.; Haguenauer-Tsapis, R.
    Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase (2001), Mol. Cell. Biol., 21, 4482-4494.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
3.4.19.12 additional information enzyme deficient strain accumulates membrane-bound ubiquitin-conjugated Fur4p Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.19.12 endosome cytosolic side Saccharomyces cerevisiae 5768
-
3.4.19.12 plasma membrane
-
 Saccharomyces cerevisiae 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.19.12 additional information Saccharomyces cerevisiae enzyme regulation ?
-
 ?
3.4.19.12 ubiquitin-protein + H2O Saccharomyces cerevisiae involved in endocytotic pathway of plasma membrane proteins ubiquitin + protein
-
 ?
3.4.19.12 ubiquitin-protein + H2O Saccharomyces cerevisiae Doap4 enzyme form plays a general role in deubiquination of membrane-bound proteins ubiquitin + protein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.19.12 Saccharomyces cerevisiae
-
 Doa4p ubiquitin isopeptidase
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.19.12 additional information enzyme regulation Saccharomyces cerevisiae ?
-
 ?
3.4.19.12 ubiquitin-Fur4p-conjugate + H2O ubiquitin is bound to the Fur4p protein via its Lys63 Saccharomyces cerevisiae ubiquitin + Fur4p
-
 ?
3.4.19.12 ubiquitin-protein + H2O involved in endocytotic pathway of plasma membrane proteins Saccharomyces cerevisiae ubiquitin + protein
-
 ?
3.4.19.12 ubiquitin-protein + H2O Doap4 enzyme form plays a general role in deubiquination of membrane-bound proteins Saccharomyces cerevisiae ubiquitin + protein
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.19.12 Doa4p ubiquitin isopeptidase
-
 Saccharomyces cerevisiae