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Literature summary extracted from

  • Bora, P.S.; Spilburg, C.A.; Lange, L.G.
    Purification to homogeneity and characterization of major fatty acid ethyl ester synthase from human myocardium (1989), FEBS Lett., 258, 236-239.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.67 0.12
-
 stearate pH 7.2 Homo sapiens
3.1.1.67 0.13
-
 arachidonate pH 7.2 Homo sapiens
3.1.1.67 0.18
-
 palmitate pH 7.2 Homo sapiens
3.1.1.67 0.2
-
 linoleate pH 7.2 Homo sapiens
3.1.1.67 0.22 0.23 oleate pH 7.2 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.67 cytosol
-
 Homo sapiens 5829
-
3.1.1.67 soluble
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.67 26000
-
 2 * 26000, SDS-PAGE Homo sapiens
3.1.1.67 54000
-
 gel filtration under nondenaturing conditions Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.67 fatty acid + ethanol Homo sapiens nonoxidative ethanol metabolism fatty acyl ethyl ester + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.67 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.67 8867fold, major enzyme form, synthase I Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.67 heart ventricular myocardium Homo sapiens
-
3.1.1.67 myocardium ventricular Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.67 additional information
-
-
 Homo sapiens
3.1.1.67 0.04433
-
 major enzyme form Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.67 arachidonate + ethanol 50% of the rate with oleate Homo sapiens ethyl arachidonate + H2O
-
 ?
3.1.1.67 fatty acid + ethanol
-
 Homo sapiens fatty acyl ethyl ester + H2O
-
 ?
3.1.1.67 fatty acid + ethanol nonoxidative ethanol metabolism Homo sapiens fatty acyl ethyl ester + H2O
-
 ?
3.1.1.67 linoleate + ethanol 65% of the rate with oleate Homo sapiens ethyl linoleate + H2O
-
 ?
3.1.1.67 oleate + ethanol highest activity Homo sapiens ethyl oleate + H2O
-
 ?
3.1.1.67 palmitate + ethanol 20% of the rate with oleate Homo sapiens ethyl palmitate + H2O
-
 ?
3.1.1.67 stearate + ethanol 22% of the rate with oleate Homo sapiens ethyl stearate + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.67 dimer 2 * 26000, SDS-PAGE Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.67 7.2
-
 assay at Homo sapiens