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Literature summary extracted from

  • Kassovska-Bratinova, S.; Fukao, T.; Song, X.Q.; Duncan, A.M.V.; Chen, H.S.; Robert, M.F.; Perez-Cerda, C.; Ugarte, M.; Chartrand, C.; et al.
    Succinyl CoA:3-oxoacid CoA transferase (SCOT): human cDNA cloning, human chromosomal mapping to 5p13, and mutation detection in a SCOT-deficient patient (1996), Am. J. Hum. Genet., 59, 519-528.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.3.5 succinyl-CoA + acetoacetate Homo sapiens rate determining step of ketolysis in extrahepatic tissues ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Homo sapiens enzyme deficiency leads to ketoacidotic crises and persistent ketosis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.3.5 Homo sapiens
-
 SCOT-deficient patients
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.3.5 fibroblast
-
 Homo sapiens
-
2.8.3.5 heart
-
 Homo sapiens
-
2.8.3.5 leukocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.3.5 succinyl-CoA + acetoacetate rate determining step of ketolysis in extrahepatic tissues Homo sapiens ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate enzyme deficiency leads to ketoacidotic crises and persistent ketosis Homo sapiens ?
-
 ?